Development of Miniaturized Sample Preparation Procedures: Towards Automation and Potential Onsite Applications

Guest Speaker:
Prof Lee Hian Kee (National University of Singapore)
Dr Sini George (School of Pharmacy, University of Reading Malaysia)
Subject Area:
Date & Time:
Wed, 8. March 2017, 13:00 h - 14:00 h
S3.24, University of Reading Malaysia - EduCity@Iskandar

Sample preparation has experienced a trend towards miniaturization over the past twenty-five years. Solid-phase microextraction (SPME), a sorbent-based approach, was the first microscale sample preparation procedure to be introduced. Soon after, a series of similar solventless or solvent-minimized methods, including solvent-based liquid-phase microextraction (LPME), followed. Miniaturized sample preparation remains a very active research field. In this talk, we shall give an account of the role our group has played since our pioneering contributions in LPME, as well as in sorbent-based (SPME-like), research. In recent years, our attention has been focused on automating miniaturized sample procedures, and integrating them seamlessly with analysis. We shall describe some of these attempts to set up fully automated analytical platforms that have the potential of being operated for on-site water analysis.


Hian Kee Lee is Professor at the Department of Chemistry, National University of Singapore (NUS). Separately, he also held the NUS Provost’s Term Chair Professorship from 2011 to 2014. Concurrently, he is affiliated with the NUS Environmental Research Institute as Principal Investigator and Executive Committee Member, and as Senior Research Fellow of the NUS Tropical Marine Science Institute. His main research interests are in microscale separation science with a specific focus on miniaturized, solvent-minimized sample preparation. More recently, his work has been centred on the development of automated integrative water sampling-sample preparation-analytical platforms for environmental applications. He has been an editor of the Journal of Chromatography A since 2010, and was an editor of Analytica Chimica Acta from 2005 to 2011. He is author or co-author of more than 370 publications and more than 340 conference presentations. Professor Lee is an elected Fellow of the Royal Society of Chemistry, the Singapore National Academy of Science, and the Academy of Sciences Malaysia. He was featured in 2013 and 2015 in The Analytical Scientist as one of the “Top 100 Most Influential People in the World of Analytical Science.”

  • Admission is free.​
  • Tea break will be served at 2:00 pm.
  • UoRM staff RSVP by responding to the internal event invitation.
  • All are welcome, RSVP by 3 March 2017.

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